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學  歷:私立高雄醫學大學醫學研究所博士(2004年)

     私立高雄醫學院醫學研究所碩士(1999年)

     國立屏東技術學院獸醫系肄業(1997年)

     私立大仁藥學專科學校藥學科畢業 1995年)

 

電子信箱:shenkuoping@yahoo.com.tw

 

聯絡電話:()08-77998216310

 

經  歷:慈惠醫護專科學校護理科兼任講師

     三民高中兼任講師

     樹德高職兼任講師

 

任教科目:幼兒生理學、生理病理學、幼兒健康照護

 

興  趣:閱讀、看電影、打球

 

研討會論文:

1.林柔軍、沈國屏、吳昆哲、趙文期、廖美玲、陳玉桂、陳瑞山、林慧麗(2009)。營養性葉酸缺乏

  於血管內皮細胞生長與分裂之影響。2009南台灣健康照護與健康產業學術研討會

  (Oral presentation)。

2.Su-Ling Hsieh, Hui-Li Lin, Bin-Nan Wu,Ing-Jun Chen, and Kuo-Ping Shen(2009).

  A Natural Isoeugenol-derived Compound Ameliorates Hyperglycemia and

  Hyperlipidemia in the High-Fat Diet-Fed Mice.

  第24屆天然藥物研討會(Poster presentation)。

3.Shen KP,Lin HL,Chen IJ, Wu BN(2009)Effect of endothelial NOS-enhancer in

  C57BL/6J mice with hyperglycemia and hyperlipidemia. The 24th Joint Annual

   Conference of Biomedical Sciences.(Poster presentation)

4.沈國屏、林慧麗(2008)。以血清素抑制劑用於敗血症治療之藥理研究。

  2008南台灣健康產業研討會(Poster presentation)。

5.沈國屏、梁至中、王琪文、吳雅芬、林郁芳、方雅鈴、陳美玲、張勝止、賴慧玲(2008)。

  幼兒園餐點供應現況之研究。2008南台灣幼兒保育研討會(Poster presentation)。

6.Shen KP, Lin HL, Chen IJ, Wu BN (2008) Eugenosedin-A prevents the

  hyperglycemia and hyperlipidemia induced by high-fat diet in C57BL/6J mice.

  The 23th  Joint Annual Conference of Biomedical Sciences.(Poster presentation)。

7.KP Shen, LW Chu, SL Hsieh, LM An, PC Wu, IJ Chen, BN Wu  (2007)

 Hypotensive and anti-aggregative effects of eugenosedin-B with serotonin and  

 α/β-adrenoceptor antagonistic activities in rat and human platelets.2007

 Annual Meeting of the Pharmaceutical Society of Taiwan. (Poster presentation)  

8.Hui-Li Lin, Kuo-Ping Shen, Shao-Fu Liao, Jing-Chuan Chen, Wen-Ing Hwang,

 Hwei-Mei Wen, Yun-Hor Chung (2007) Folate deficiecy in human peripheral

 lymphocytes induces autoimmunity phenomena. The 10th Asian Congress of

 Nutrition. (Poster presentation)

9.沈國屏、梁至中 (2007)。以維生素C用於敗血症治療之藥理研究。

 2007南台灣幼兒保育研討會 (Poster presentation)

10.Shen KP, Lin HL, Wu BN, Chen IJ (2007) Comparison of 3 isoeugenol-based

 derivatives, involved in inhibiting serotonergic/adrenergic receptor, lipid

 peroxidation and platelet aggregation activities. The 22th Joint Annual

 Conference of Biomedical Sciences. (Poster presentation)

11.沈國屏、梁至中 (2006)。異丁香醇衍生物對於大鼠心血管作用之研究。

  2006南台灣幼兒保育研討會 (Poster presentation)

12.Shen KP, Chen IJ, Wu BN. (2004) Eugenosedin-A inhibits LPS-induced

  expression of iNOS/COX-2 and protects from oxidative injury. The 19th

  Joint Annual Conference of Biomedical Sciences. (Poster presentation)

13.Shen KP, Wu BN, Lo YC, Yang RC, Liu HW, Chen IJ. (2003) Ugosedin protects

  against LPS-induced hypotension and cytokine formation, involved in

  regulation of adrenergic and serotonergic neuron systems. The 18th Joint

  Annual Conference of Biomedical Sciences. (Poster presentation)

14.Tsai PL, Lo YC, Shen KP, Ann LM, Wu YC, Lai YH, Chen IJ. (2003) Effects of

  San-Fan-Sei-Sin Tang on LPS-induced hypotension, cytokines formation and

  expression of inducible nitric oxide synthase and cyclooxygenase-2.

  The 18th Joint Annual Conference of Biomedical Sciences. (Poster presentation)

15.Wang JJ, Shen KP, Ann LM, Chen IJ, Lo YC. (2003) WJ-1 displays a-adrenergic

  and serotonin antagonist activities. The 18th Joint Annual Conference of

  Biomedical Sciences. (Poster presentation)

16.Yeh CH, Lin RJ, Shen KP, Chen IJ, Wu BN. (2003) Xanthine-based KMUP-1, 3, 4

  upregulate eNOS expression in human umbilical vein endothelial cells. The

  18th Joint Annual Conference of Biomedical Sciences. (Poster presentation)

17.Chen IC, Wu BN, Lin RJ, Shen KP, Chen IJ. (2002) Pharmacological profile of  

  KMUP-3 and KMUP-4, potent xanthine-derived vascular smooth muscle relaxant

   with potassium channel opening properties, in isolated rat aorta. The 17th

   Joint Annual Conference of Biomedical Sciences. (Poster presentation)

18.Lin RJ, Wu BN, Chen IC, Shen KP, Chen IJ. (2002) KMUP-3: a trachea relaxant

  associated with soluble guanylyl cyclase activation and K+ channel activities.

  The 17th Joint Annual Conference of Biomedical Sciences. (Poster presentation)

19.Chu LW, Wu BN, Shen KP, Lin RJ, Chen IJ. (2002) KMUP-417: a potent serotonin  

  receptor and a2-adrenoceptor antagonist with antiplatelet aggregation

   activity.The 17th Joint Annual Conference of Biomedical Sciences.

   (Poster presentation)

 

期刊論文

1.Kuo-Ping Shen, Hui-Li, Su-Ling Hsieh, Aij-Lie Kwan, Ing-Jun Chen,

  Bin-Nan Wu.(2009)Eugenosedin-A prevention of hyperglycemia, hyperlopdemia

  and lipid peroxidation in C57BL/6J mice fed with high-fat diet. J Pharm

  Pharmacol61:517-525.(SCI)

2.Kuo-Ping Shen,Li-Wen Chu,Su-Ling Hsieh,Li-Mei An,Ing-Jun Chen,Bin-Nan

  Wu.(2008)Hypotensive and Anti-aggregative Effects of Eugenosedin-B with

  Serotonin and a/b -Adrenoceptor Antagonistic Activities in Rats and Human

  Platelets .J Cardiovasc Pharmacol51:154-161.(SCI)

3.陳彥廷、梁至中、沈國屏(2007)。高一數學補修學分班試行合作學習成效之探討。

 親民學報,第十三期,P103-120

4.Shen KP, Liou SF, Hsieh SL, Chen IJ, Wu BN. (2007) Eugenosedin-A

 amelioration of lipopolysaccharide-induced up-regulation of p38 MAPK,

 inducible nitric oxide synthase and cyclooxygenase-2. J Pharm Pharmacol

 59:879-889. (SCI)

5.沈國屏、梁至中 (2006)。異丁香醇衍生物對於大鼠心血管作用之研究。

 幼兒保育學刊,第四期,P243-258

6.Shen KP, Lo YC, Yang RC, Liu HW, Chen IJ, Wu BN. (2005) Antioxidant

 eugenosedin-A protects against lipopolysaccharide-induced hypotension,

 hyperglycaemia and cytokine immunoreactivity in rats and mice. J Pharm

 Pharmacol 57:117-25. (SCI)

7.Lo YC, Tsai PL. Huang YB, Shen KP, Tsai TH, Wu YC, Lai YH, Chen IJ.

 (2005) San-Huang-Xie-Xin-Tang reduces lipopolysaccharides-induced

 hypotension and inflammatory mediators. J Ethnopharmacol 96:99-106. (SCI)

8.Lo YC, Wang CC, Shen KP, Wu BN, Yu KL, Chen IJ. (2004) Urgosedin inhibits

 hypotension, hypoglycemia, and pro-inflammatory mediators induced by

 lipopolysaccharide. J Cardiovasc Pharmacol 44:363-71. (SCI)

9.Shen KP, Chiu CC, Chen SJ, Chen IJ, Wu BN. (2004) Hypotensive effects of

 eugenosedin-A with serotonin, - and -adrenoceptor antagonistic activities

 in spontaneously hypertensive and normotensive rats.

 Pharmacology 71:91-101. (SCI)

10.Wu BN, Lin RJ, Lo YC, Shen KP, Wang CC, Lin YT, Chen IJ. (2004) KMUP-1, a

 xanthine derivative, induces relaxation of guinea-pig isolated trachea:

 the role of the epithelium, cyclic nucleotides and K+ channels. Br J

 Pharmacol 142:1105-14. (SCI)

11.Lin RJ, Wu BN, Lo YC, Shen KP, Lin YT, Huang CH, Chen IJ. (2002) KMUP-1

 relaxes rabbit corpus cavernosum smooth muscle in vitro and in vivo:

 involvement of cyclic GMP and K+ channels. Br J Pharmacol 135:1159-66. (SCI)

12.Lin RJ, Wu BN, Shen KP, Huang CH, Liu ZI, Lin CY, Cheng CJ, Chen IJ.

 (2002) Xanthine-analog, KMUP-2, Enhances cyclic GMP and K+ channel activities

 in rabbit aorta and corpus cavernosum with associated penile erection.

 Drug Development Research 55:162-172. (SCI)

13.Wu BN, Lin RJ, Lin CY, Shen KP, Chiang LC, Chen IJ. (2001) A xanthine-based

 KMUP-1 with cyclic GMP enhancing and K+ channels opening activities in rat

 aortic smooth muscle. Br J Pharmacol 134:265-74. (SCI)

14.Shen KP, Lin RJ, Lin CY, Chiang LC, Lai WT, Cheng CJ, Chen IJ, Wu BN. (2000)

 An unique xanthine derivative KMCP-98 with activation of adenosine receptor

 subtypes. Gen Pharmacol 35:47-57. (SCI)

15.Wu BN, Shen KP, Lin RJ, Huang YC, Chiang LC, Lo YC, Lin CY, Chen IJ. (2000)

 Lipid solubility of vasodilatory vanilloid-type beta-blockers on the functional

 and binding activities of beta-adrenoceptor subtypes.

 Gen Pharmacol 34:321-8. (SCI)

 

 

研究計畫:

1.九十六年度教師專題研究計畫

 計畫名稱:利用ascorbic acid治療敗血症引發心血管病變之研究

 計畫編號:MH-96-DEC-003

2.九十六年度教師產學合作計畫

 計畫名稱:利用aminoguanidine治療敗血症引發心血管病變之研究

 計畫編號:96-ME-DEC-IAC-002

3.九十五年度教師專題研究計畫

 計畫名稱:比較異丁香醇衍生物,statin類藥物與腎上腺乙型阻斷劑對於治療高血脂症效用之研究

 計畫編號:NSC95-2320-B-276-003

4.九十五年度教師專題研究計畫

 計畫名稱:比較一系列由異丁香醇衍生之新化合物eugenosedins之要理活性

 計畫編號:MH-95-DEC-008